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Creatinine

Quick answer

What is Creatinine?

Creatinine reflects kidney filtration capacity (via eGFR, calculated from creatinine, age, and sex). Affected by muscle mass — heavily-muscled men run higher creatinine without kidney disease.

Units:
µmol/L
Reference range:
60-110 µmol/L (men)
Sample:
Venous blood (serum)
Category
Kidney
Units
µmol/L
Reference range
60-110 µmol/L (men)

What does a high Creatinine result mean?

Reduced kidney function, dehydration, high muscle mass, certain medications. Persistent elevation with reduced eGFR warrants investigation.

What does a low Creatinine result mean?

Low muscle mass, severe malnutrition.

Why does Creatinine matter?

Kidney function silently declines. Annual creatinine + eGFR catches it before it's a problem.

References

  1. [1]KDIGO Clinical Practice Guideline for the Evaluation of CKDPubMed / Kidney Int
  2. [2]Clinical Methods: The History, Physical, and Laboratory ExaminationsNCBI Bookshelf

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